Dolo 500 tablet is used to reduce fever and relieve pain. It contains paracetamol (also known as Acetaminophen) as its active ingredient that works by inhibiting the action of certain substances that causes pain and acts on the brain centre which is responsible for controlling body temperature. Use of Dolo 500 tablet for a prolonged period and in high doses is associated with serious liver damage. The chances of you experiencing any side effects with the Dolo 500 tablet is mostly rare but sometimes you may experience skin rash or itching. If you experience any allergic symptoms after taking this medicine, then report to a doctor. duration and in high doses is associated with serious liver damage.